That is officially known as Can o' Worms Question #574... Better or worse, like everything "saxophone", is subjective. In terms of sound it's more about what is coming in contact with the reed than how it tightens. The more mass coming in contact with the reed (and the more pressure applied) - the more "dead" the reed becomes. Better/worse? Depends on your objective. Some people like a deader response - particularly classical players moreso than jazz players. Some people like a more lively or bright sounding set-up and then they might prefer a Rovner Eddie Daniels lig or a Bonade which has thin rails instead of full lig to reed contact. One complaint I have about single screw ligs (where the screw and applied pressure is perpendicular to the reed and table) is that the manufacturers for whatever lame reason don't make the threads fine enough and it can be difficult to fine tune the amount of pressure being applied to hold the reed in place - it's either too loose or too firm. Put cork grease on the lig screws in any case to smooth the action of it.