i hate to say it, but the D will always be out of tune as well as the E, it is in the design of the saxophone. no company can get it down. and i have always had intonation problems with yanis. they are great horns over all, but the altos are all over the place with intonation, thats my experience with them anyway. dont ever count on a horn to be in tune naturally. count on the horn to be consisntly out of tune. my vintage selmer has intonation that is pretty shotty. but i have the needle up and down because i know the tendencies on each note and adjust for each note

"Must i keep changing my embrocure everytime i play this two notes?" Yes and No Yes you need to be constantly changing to make up for the short comings of the horn. And all instruments have intonation issues. But don't think of it as changings your embrocure. Think of it as changing the your air and your soft pallete, throat, and small muscles that you can even feel. But you lips should not be tightening of loosening from note to note. Mostly just practice with a tuner, and always be listening to your self. If you can hear that you are out of tune you will start to fix what is wrong. There have also been a few discussion on mouthpiece excercises. They may help a lot with your intonation. Enjoy

D is VERY sharp and it takes practice tuning it to get it where you do fix it by lipping it down a little automatically without thinking. Best note to tune on is either an F or F#...I forgot which one but they both work.

One tip that might help is to NOT tune every note perfectly. Don't get every note in tune except 2-3 notes which are off the chart.